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New Tripeptide Derivatives Asperripeptides A-C from Vietnamese Mangrove-Derived Fungus
- Source :
- Marine Drugs
- Publication Year :
- 2021
-
Abstract
- Three new tripeptide derivatives asterripeptides A–C (1–3) were isolated from Vietnamese mangrove-derived fungus Aspergillus terreus LM.5.2. Structures of isolated compounds were determined by a combination of NMR and ESIMS techniques. The absolute configurations of all stereocenters were determined using the Murfey’s method. The isolated compounds 1–3 contain a rare fungi cinnamic acid residue. The cytotoxicity of isolated compounds against several cancer cell lines and inhibition ability of sortase A from Staphylococcus aureus of asterripeptides A–C were investigated.
- Subjects :
- Aquatic Organisms
Staphylococcus aureus
secondary metabolites
mangrove-derived fungi
Antineoplastic Agents
Microbial Sensitivity Tests
Article
diketopiperazines
Anti-Bacterial Agents
tripeptide derivatives
marine-derived fungi
Magnoliopsida
Aspergillus
sortase A
Cell Line, Tumor
Animals
Humans
cytotoxicity
Peptides
cinnamic acid
Subjects
Details
- ISSN :
- 16603397
- Volume :
- 20
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Marine drugs
- Accession number :
- edsair.pmid..........edb361be8cc82b9ccaa83a113b61b4bc