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Authors :
Fernando H, Centeno
Todd, Lasco
Asim A, Ahmed
Mayar, Al Mohajer
Source :
Open Forum Infectious Diseases
Publication Year :
2021

Abstract

We present 10 patients with Rickettsia typhi infection in whom next-generation sequencing of microbial cell-free deoxyribonucleic acid (mcfDNA) was used as a diagnostic tool. Rickettsia typhi mcfDNA was detected in all cases and was more rapid and specific than rickettsial serology. Rickettsia typhi mcfDNA impacted antibiotic management in 50% of patients.

Subjects

Subjects :
animal structures
AcademicSubjects/MED00290
Brief Report
bacteria
murine typhus
next-generation sequencing
Rickettsia typhi
bacterial infections and mycoses
complex mixtures
clinical characteristics

Details

ISSN :
23288957
Volume :
8
Issue :
7
Database :
OpenAIRE
Journal :
Open forum infectious diseases
Accession number :
edsair.pmid..........e55fa7e5e69c253e2587ab15568d366b

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Authors Abstract Subjects Details