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Prostanoid EP

Authors :
Hsin-Hsien, Li
Hsao-Hsun, Hsu
Gwo-Jyh, Chang
I-Chen, Chen
Wan-Jing, Ho
Pei-Chen, Hsu
Wei-Jan, Chen
Jong-Hwei S, Pang
Chung-Chi, Huang
Ying-Ju, Lai
Source :
American journal of physiology. Lung cellular and molecular physiology. 314(3)
Publication Year :
2017

Abstract

Prostacyclin agonists that bind the prostacyclin receptor (IP) to stimulate cAMP synthesis are effective vasodilators for the treatment of idiopathic pulmonary arterial hypertension (IPAH), but this signaling may occur through nuclear peroxisome proliferator-activated receptor-γ (PPARγ). There is evidence of scant IP and PPARγ expression but stable prostanoid EP

Details

ISSN :
15221504
Volume :
314
Issue :
3
Database :
OpenAIRE
Journal :
American journal of physiology. Lung cellular and molecular physiology
Accession number :
edsair.pmid..........e035e8c672c6b89984e4ec0a866a18d8