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Enzymological Characterization of
- Source :
- Journal of medicinal chemistry.
- Publication Year :
- 2023
-
Abstract
- The applicability of radioligands for targeted endoradionuclide therapy is limited due to radiation-induced toxicity to healthy tissues, in particular to the kidneys as primary organs of elimination. The targeting of enzymes of the renal brush border membrane by cleavable linkers that permit the formation of fast eliminating radionuclide-carrying cleavage fragments gains increasing interest. Herein, we synthesized a small library of
Details
- ISSN :
- 15204804
- Database :
- OpenAIRE
- Journal :
- Journal of medicinal chemistry
- Accession number :
- edsair.pmid..........df87a31266f43451cd5bab86b66997b1