The

Authors :: Carolina, Herrera
Mackenzie L, Cottrell
John, Prybylski
Angela D M, Kashuba
Ronald S, Veazey
Javier, García-Pérez
Natalia, Olejniczak
Clare F, McCoy
Paul, Ziprin
Nicola, Richardson-Harman
José, Alcami
Karl R, Malcolm
Robin J, Shattock
Source :: iScience. 25(6)
Publication Year :: 2021
Abstract: Non-human primates (NHP) are widely used for the pre-clinical assessment of antiretrovirals (ARVs) for HIV treatment and prevention. However, the utility of these models is questionable given the differences in ARV pharmacology between humans and macaques. Here, we report a model based on

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