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Research into the Bioengineering of a Novel α-Conotoxin from the Milked Venom of

Authors :
Sean, Wiere
Christopher, Sugai
Michael J, Espiritu
Vincent P, Aurelio
Chloe D, Reyes
Nicole, Yuzon
Randy M, Whittal
Jan, Tytgat
Steve, Peigneur
Jon-Paul, Bingham
Source :
International journal of molecular sciences. 23(20)
Publication Year :
2022

Abstract

The marine cone snail produces one of the fastest prey strikes in the animal kingdom. It injects highly efficacious venom, often causing prey paralysis and death within seconds. Each snail has hundreds of conotoxins, which serve as a source for discovering and utilizing novel analgesic peptide therapeutics. In this study, we discovered, isolated, and synthesized a novel α3/5-conotoxins derived from the milked venom of

Details

ISSN :
14220067
Volume :
23
Issue :
20
Database :
OpenAIRE
Journal :
International journal of molecular sciences
Accession number :
edsair.pmid..........dd103b3ba4eee863482e3ab058cd2884