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Possible neuroprotective effects of amide alkaloids from

Authors :
Ahmed, Othman
Ahmed M, Sayed
Yhiya, Amen
Kuniyoshi, Shimizu
Source :
RSC advances. 12(29)
Publication Year :
2022

Abstract

In Alzheimer's disease (AD), the accumulation of amyloid-β plaques, overactivity of MAO-B, and phosphorylated tau protein in the central nervous system result in neuroinflammation and cognitive impairments. Therefore, the multi-targeting of these therapeutic targets has emerged as a promising strategy for the development of AD treatments. The current study reports the isolation and identification of seven amide alkaloids, namely

Details

ISSN :
20462069
Volume :
12
Issue :
29
Database :
OpenAIRE
Journal :
RSC advances
Accession number :
edsair.pmid..........dafafd6c44150856b7e109a0aaad27ef