[Effect of a single dose of nifedipine on pulmonary hypertension measured by doppler echocardiography]

In 14 patients with chronic obstructive pulmonary disease and symptoms of cor pulmonale a single dose of nifedypine was administered and Doppler echocardiography measurements were performed to evaluate a degree of pulmonary hypertension. An acceleration time (AcT) and mean pulmonary artery pressure (MPAP) before and after 20 mg dose of nifedypine were determined, parallel with evaluation of systolic and diastolic blood pressure. In performed examinations it was documented that 20 mg dose of nifedypine induced a decrease of MPAP in observed patients.