A hydrolysate of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) suppresses Ca

Authors :: Fumiko, Sekiguchi
Nene, Koike
Yasuhiro, Shimada
Kaho, Sugimoto
Hiroshi, Masuda
Takashi, Nakamura
Hiroaki, Yamaguchi
Genzoh, Tanabe
Shinsuke, Marumoto
Yoshihito, Kasanami
Maho, Tsubota
Tsuyako, Ohkubo
Shigeru, Yoshida
Atsufumi, Kawabata
Source :: Redox biology. 59
Publication Year :: 2022
Abstract: Poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132), an organogermanium, is hydrolyzed to 3-(trihydroxygermyl)propanoic acid (THGP) in aqueous solutions, and reduces inflammation, pain and cancer, whereas the underlying mechanisms remain unknown. Sulfides including H

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