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Superfast Synthesis of Stabilized Silver Nanoparticles Using Aqueous
- Source :
- Molecules
- Publication Year :
- 2021
-
Abstract
- Green synthesis of silver nanoparticles (AgNPs) was synthesized from fresh garlic extract coupled with isoniazid hydrazide (INH), a commonly used antibiotic to treat tuberculosis. A molecular docking study conducted with the selected compounds compared with anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis. The aqueous extract of garlic was prepared and mixed with silver nitrate (AgNO3) solution for the superfast synthesis of stable AgNPs. INH was then conjugated with AgNPs at different ratios (v/v) to obtain stable INH-AgNPs conjugates (AgNCs). The resulting AgNCs characterized by FTIR spectra revealed the ultrafast formation of AgNPs (
- Subjects :
- silver nanoparticles
garlic extract
Binding Sites
Silver
Plant Extracts
Spectrum Analysis
green synthesis
Phytochemicals
isoniazid hydrazide
Antitubercular Agents
Metal Nanoparticles
Green Chemistry Technology
Chemistry Techniques, Synthetic
molecular docking
Molecular Dynamics Simulation
Ligands
Article
Molecular Docking Simulation
Structure-Activity Relationship
Hydrazines
Drug Stability
nanoconjugates
Isoniazid
Garlic
Protein Binding
Subjects
Details
- ISSN :
- 14203049
- Volume :
- 27
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Molecules (Basel, Switzerland)
- Accession number :
- edsair.pmid..........d5f271ab46b7aaa69c195ebf7930e167