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Metabolic flux ratio analysis by parallel

Authors :
Enrico, Orsi
Jules, Beekwilder
Siebe, Peek
Gerrit, Eggink
Servé W M, Kengen
Ruud A, Weusthuis
Source :
Metabolic engineering. 57
Publication Year :
2019

Abstract

Metabolic engineering for increased isoprenoid production often benefits from the simultaneous expression of the two naturally available isoprenoid metabolic routes, namely the 2-methyl-D-erythritol 4-phosphate (MEP) pathway and the mevalonate (MVA) pathway. Quantification of the contribution of these pathways to the overall isoprenoid production can help to obtain a better understanding of the metabolism within a microbial cell factory. Such type of investigation can benefit from

Details

ISSN :
10967184
Volume :
57
Database :
OpenAIRE
Journal :
Metabolic engineering
Accession number :
edsair.pmid..........d5ad28a49248f6d930fcd0f609a824ef