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KRAS

Authors :
Zhi-Wei, Zhou
Chiara, Ambrogio
Asim K, Bera
Qing, Li
Xing-Xiao, Li
Lianbo, Li
Jieun, Son
Sudershan, Gondi
Jiaqi, Li
Emily, Campbell
Hua, Jin
Jeffrey J, Okoro
Cheng-Xiong, Xu
Pasi A, Janne
Kenneth D, Westover
Source :
Cancer research. 80(17)
Publication Year :
2020

Abstract

Assembly of RAS molecules into complexes at the cell membrane is critical for RAS signaling. We previously showed that oncogenic KRAS codon 61 mutations increase its affinity for RAF, raising the possibility that KRAS

Details

ISSN :
15387445
Volume :
80
Issue :
17
Database :
OpenAIRE
Journal :
Cancer research
Accession number :
edsair.pmid..........d3998258f0e28daae6ad7291884b9878