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[The therapeutic activity of stepronin in viral hepatitis]

Authors :
G, Bosio
C, Bramato
B, Salassa
G, Andreoni
R, Magliocca
Source :
Minerva medica. 73(41)
Publication Year :
1982

Abstract

The therapeutic effect of stepronin in 5% glucosate solution has been evaluated in 55/110 viral hepatitis cases (10/55 of A type, 37/55 of B type and 8/55 of nA type nB type), versus other cases (8/55 of A type, 40/55 of B type of 7/55 of nA nB type), treated with 5% glucose solution only. In 18/110 viral hepatitis case of A type, final results with the two different therapies have not shown statistically significantly changes and were comparable. Particularly favourable, in the patients treated, the results obtained in viral hepatitis of B type and nA nB type, were very significant statistically at the end of therapy. In particular, the 2 transaminasic activities had a beneficial influence. Tolerance was very good: only in there cases nettlerash was observed and therapy interrupted in one patient. Therefore the validity of this sulphydryl pro-drug in the treatment of acute viral hepatitis of B and nA and nB type is confirmed.

Details

ISSN :
00264806
Volume :
73
Issue :
41
Database :
OpenAIRE
Journal :
Minerva medica
Accession number :
edsair.pmid..........d1a08aa76ad427ab7d101e267a7dc10c