CLN3 is required for the clearance of glycerophosphodiesters from lysosomes

Authors :: Nouf N, Laqtom
Wentao, Dong
Uche N, Medoh
Andrew L, Cangelosi
Vimisha, Dharamdasani
Sze Ham, Chan
Tenzin, Kunchok
Caroline A, Lewis
Ivonne, Heinze
Rachel, Tang
Christian, Grimm
An N, Dang Do
Forbes D, Porter
Alessandro, Ori
David M, Sabatini
Monther, Abu-Remaileh
Source :: Nature. 609(7929)
Publication Year :: 2020
Abstract: Lysosomes have many roles, including degrading macromolecules and signalling to the nucleus

Subjects :: Lysosomal Storage Diseases
Mice
Membrane Glycoproteins
Neuronal Ceroid-Lipofuscinoses
Inositol Phosphates
Animals
Humans
Esters
Glycerophospholipids
Child
Lysosomes
Biomarkers
Molecular Chaperones

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