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Comparison of the adverse events of anterior cervical disc replacement versus anterior cervical discectomy and fusion
- Source :
- Medicine
- Publication Year :
- 2018
- Publisher :
- Wolters Kluwer Health, 2018.
-
Abstract
- Supplemental Digital Content is available in the text<br />Background: In the current surgical therapeutic regimen for symptomatic cervical degenerative disc disease, both anterior cervical discectomy and fusion (ACDF) and anterior cervical disc replacement (ACDR) are still widely accepted. However, many complications exist in both surgeries. Therefore, this study aims to compare the adverse events between ACDR and ACDF, and provide vital evidence-based guidance for spine surgeons and designers to evaluation of prognosis and improvement of dynamic devices. Methods: A systematic review and meta-analysis that will be performed according to the PRISMA. The electric database of PubMed, Medline, Embase, Google Scholar, and Cochrane library will be systematic search. A standard data form will be used to extract the data of included studies. We will assess the studies according to the Cochrane Handbook for Systematic Reviews of Interventions, and perform analysis in RevMan 5.3 software. Fixed effects models will be used for homogeneity data, while random-effects will be used for heterogeneity data. The overall effect sizes will be determined as weighted mean difference (WMD) for continuous outcomes and relative risk (RR) for dichotomous outcomes. Result: The results of this study will be disseminated via international or national conferences, or submit to peer-reviewed journal in spinal field. Conclusion: The conclusion of this study will provide key evidence-based guidance for spine surgeons and designers to the evaluation of prognosis and improvement of dynamic devices.
- Subjects :
- Total Disc Replacement
Intervertebral Disc Degeneration
Risk Assessment
anterior cervical disc replacement
Outcome and Process Assessment, Health Care
Postoperative Complications
Spinal Fusion
Research Design
Study Protocol Systematic Review
ComputingMethodologies_DOCUMENTANDTEXTPROCESSING
Cervical Vertebrae
Humans
protocol
anterior cervical discectomy and fusion
Research Article
Diskectomy
Randomized Controlled Trials as Topic
Subjects
Details
- Language :
- English
- ISSN :
- 15365964 and 00257974
- Volume :
- 97
- Issue :
- 16
- Database :
- OpenAIRE
- Journal :
- Medicine
- Accession number :
- edsair.pmid..........d05738b08ccd6f57e6ac7aa4a56d1564