[Fundamental and clinical studies on T-1982 (cefbuperazone) in the field of obstetrics and gynecology]

T-1982 (cefbuperazone), a new cephamycin antibiotic, was fundamentally and clinically studied in the field of obstetrics and gynecology. The following results were obtained. The concentrations of T-1982 in arterial and venous blood and genitalia following intravenous injection were measured. The results demonstrated favourable transfer of the drug into various internal genital organs. T-1982 was administered to 12 patients. The efficacy rate was 75.0%, that is to say, good in 9 cases. No side effects were noted in any cases. It is, therefore, presumed that T-1982 is a useful drug for the infectious diseases in the field of obstetrics and gynecology although the number of subjects was not so large in this study.