Triazolopyridine ethers as potent, orally active mGlu

Authors :: Mendi A, Higgins
Lawrence R, Marcin
F, Christopher Zusi
Robert, Gentles
Min, Ding
Bradley C, Pearce
Amy, Easton
Walter A, Kostich
Matthew A, Seager
Clotilde, Bourin
Linda J, Bristow
Kim A, Johnson
Regina, Miller
John, Hogan
Valerie, Whiterock
Michael, Gulianello
Meredith, Ferrante
Yanling, Huang
Adam, Hendricson
Andrew, Alt
John E, Macor
Joanne J, Bronson
Source :: Bioorganicmedicinal chemistry. 25(2)
Publication Year :: 2016
Abstract: Triazolopyridine ethers with mGlu

Subjects :: Male
Models, Molecular
Dose-Response Relationship, Drug
Molecular Structure
Pyridines
Administration, Oral
Haplorhini
Triazoles
Receptors, Metabotropic Glutamate
Rats
Mice, Inbred C57BL
Rats, Sprague-Dawley
Disease Models, Animal
Mice
Structure-Activity Relationship
Allosteric Regulation
Schizophrenia
Animals
Ethers

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