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The impact of the halogen bonding on D
- Source :
- Bioorganicmedicinal chemistry. 25(14)
- Publication Year :
- 2016
-
Abstract
- A series of azinesulfonamides of long-chain arylpiperazine derivatives with semi-rigid alkylene spacer was designed, synthesized, and biologically evaluated using in vitro methods for their affinity for dopaminergic D
- Subjects :
- Male
Sulfonamides
Binding Sites
Receptors, Dopamine D2
Motor Activity
Ligands
Antidepressive Agents
Piperazines
Protein Structure, Tertiary
Molecular Docking Simulation
Inhibitory Concentration 50
Mice
Structure-Activity Relationship
Halogens
Receptors, Serotonin
Receptor, Serotonin, 5-HT1A
Animals
Dizocilpine Maleate
Maze Learning
Antipsychotic Agents
Subjects
Details
- ISSN :
- 14643391
- Volume :
- 25
- Issue :
- 14
- Database :
- OpenAIRE
- Journal :
- Bioorganicmedicinal chemistry
- Accession number :
- edsair.pmid..........c376caf6305fe8906d13d7ec1b733138