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Risk factors for complications of radiation therapy on tissue expander breast reconstructions
- Source :
- The breast journal. 18(1)
- Publication Year :
- 2011
-
Abstract
- Radiation therapy has been shown to increase complication rates of tissue expander/implant breast reconstructions. The purpose of this study was to evaluate patient characteristics to assess their impact on complications. A retrospective review of patients who underwent mastectomy plus tissue expander/implant reconstruction from January 2000 to December 2006 was performed. The main outcome of interest was the development of postoperative complications. Analyses were performed to detect risk factors for complications. A total of 560 patients were included in the study. A total of 385 patients underwent unilateral and 174 underwent bilateral tissue expander/implant reconstructions, for a total of 733 reconstructions. A total complication rate of 31.8% and a major complication rate of 24.4% were calculated. The risk factors associated with a significantly increased incidence of complications were age greater than 50 years, body mass index (BMI) greater than 30, and radiation. Women younger than 50 years had a complication rate of 28.4%, whereas women older than 50 years had a complication rate of 37.0%. Women with a BMI less than 30 had a complication rate of 27.5%, whereas women with a BMI greater than 30 had a complication rate of 49%. The major complication rate in nonradiated and radiated patients was 21.2% and 45.4%, respectively. Despite higher complication rates, tissue expander/implant reconstructions were successful in 70.1% of radiated patients. Based on this study, the ideal radiated patient would have a BMI less than 30 and be younger than 50 years of age to maximize the likelihood of a successful tissue expander/implant reconstruction.
- Subjects :
- Radiotherapy
Breast Implants
Tissue Expansion
Age Factors
Tissue Expansion Devices
Breast Neoplasms
Middle Aged
Body Mass Index
Logistic Models
Postoperative Complications
Treatment Outcome
Risk Factors
Odds Ratio
Humans
Female
Radiotherapy, Adjuvant
Breast Implantation
Mastectomy
Follow-Up Studies
Retrospective Studies
Subjects
Details
- ISSN :
- 15244741
- Volume :
- 18
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- The breast journal
- Accession number :
- edsair.pmid..........b9b7e04eec3cda1e11837847da0ed2af