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[Clinical analysis of salivary malignant pleomorphic adenoma--a report of 95 cases]
- Source :
- Ai zheng = Aizheng = Chinese journal of cancer. 25(9)
- Publication Year :
- 2006
-
Abstract
- Malignant pleomorphic adenoma is rare with extensive location, which makes it difficult to evaluate the efficacy of the treatments. This study was to summarize the clinical features of salivary malignant pleomorphic adenoma, and thus to explore the treatment principle and efficacy of the treatment.Clinical data of 95 salivary malignant pleomorphic adenoma patients, treated in Cancer Center, Sun Yat-sen University from May 1970 to Oct. 2000, were analyzed retrospectively. The overall cumulative survival rate was estimated using life table method by SPSS10.0 software. Survival curves were compared with Gehan method.The 5-, 10-, and 15-year overall survival rates of the 95 patients were (64.9+/-4.9)%, (56.3+/-5.4)%, and (47.8+/-6.1)%, respectively. The 5-and 10-year disease-specific survival rates for the patients received surgery (51 cases), surgery plus radiotherapy (35 cases) were 76.1%, 63.7% and 69.9%, 50.8%, respectively, but the 5-and 10-year disease-specific survival rates for the patients received radiotherapy only, chemotherapy only and radiochemotherapy (4 cases) were all 0.Surgery or surgery-dominated multi-modality are the principal treatment modalities for salivary malignant pleomorphic adenoma. The efficacy of surgery and surgery plus radiotherapy is better than non-surgery treatments.
- Subjects :
- Adult
Aged, 80 and over
Male
Adolescent
Adenoma, Pleomorphic
Middle Aged
Salivary Gland Neoplasms
Combined Modality Therapy
Parotid Neoplasms
Submandibular Gland Neoplasms
Survival Rate
Child, Preschool
Antineoplastic Combined Chemotherapy Protocols
Humans
Female
Child
Aged
Follow-Up Studies
Retrospective Studies
Subjects
Details
- Volume :
- 25
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Ai zheng = Aizheng = Chinese journal of cancer
- Accession number :
- edsair.pmid..........b83d70d92cb24167708e3be31a746821