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[Implantable insulin pump: the first step towards an artificial pancreas]
- Source :
- Annales de chirurgie. 48(11)
- Publication Year :
- 1994
-
Abstract
- Recent improvements in miniaturization of implantable pumps and the ability of their control by teletransmission allow implantation of autonomous pumps which administer insulin into the peritoneal cavity. Fifty-six patients with diabetes mellitus underwent implantation of 66 pumps with a mean function life of 21.8 months per patient. No patient has died to date. Tolerance of implanted components was good. Morbidity was limited to local events, in this series 4 cutaneous erosions, two of them leading to final pump explantation. Mean global blood-sugar, pre- and post-prandial blood-sugar, and glycosylated hemoglobin assays were all lower versus pre-implantation assays. A statistically significant difference was demonstrated regarding mean global blood-sugar. The frequency of severe hypoglycemia incidents (2 in our series) and biochemical hypoglycemia (blood-sugar65 mg/100 ml) was decreased, representing a major benefit of the technique. The patients well-being and quality of life were notably improved. Implantable insulin-pump may be offered as alternative treatment to conventional insulin-therapy, especially in cases of diabetes which are difficult to control and particularly in cases with frequent hypoglycemic malaise.
Details
- Language :
- French
- ISSN :
- 00033944
- Volume :
- 48
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Annales de chirurgie
- Accession number :
- edsair.pmid..........b652e8eb2e8f49b2c0fbb063f15f2320