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Liraglutide + PYY
- Source :
- Journal of clinical medicine. 11(3)
- Publication Year :
- 2021
-
Abstract
- Treatment options for NAFLD are still limited. Bariatric surgery, such as Roux-en-Y gastric bypass (RYGB), has been shown to improve metabolic and histologic markers of NAFLD. Glucagon-like-peptide-1 (GLP-1) analogues lead to improvements in phase 2 clinical trials. We directly compared the effects of RYGB with a treatment using liraglutide and/or peptide tyrosine tyrosine 3-36 (PYYObese male Wistar rats (high-fat diet (HFD)-induced) were randomized into the following treatment groups: RYGB, sham-operation (sham), liraglutide (0.4 mg/kg/day), PYYRYGB and liraglutide+PYYThe combination therapy of liraglutide+PYY
Details
- ISSN :
- 20770383
- Volume :
- 11
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of clinical medicine
- Accession number :
- edsair.pmid..........b5cb86dbb0ce3ffe6036763b52c2b814