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[Thymic carcinoid tumor revealed by a Cushing's syndrome: usefulness of positron emission tomography]

Authors :
E, Gomard-Mennesson
P, Sève
E, De La Roche
S, Collardeau-Frachon
C, Lombard-Bohas
C, Broussolle
Source :
La Revue de medecine interne. 29(9)
Publication Year :
2007

Abstract

Ectopic adrenocorticotropic (ACTH) syndrome is a rare condition, generally due to lung or carcinoid tumors. 18-fluorodeoxy-glucose positron emission tomography ((18)FDG-PET) can be useful where conventional localization techniques often fail. A 50-year-old man presented with sudden diffuse oedema, hypokaliemic alkalosis, Diabetes mellitus and high serum levels of ACTH and cortisol. Ectopic ACTH syndrome was confirmed leading to ketoconazole treatment. Chest-computed tomography only revealed an aspecific anterior mediastinal nodule that was hypermetabolic on the whole body-(18)FDG-PET. A thymic tumor was suspected and the patient had a thymectomy that revealed an atypical carcinoid tumor with pleural carcinosis. The postoperative course was favorable with clinical and biochemical remission of neoplastic Cushing's syndrome.

Details

Language :
French
ISSN :
02488663
Volume :
29
Issue :
9
Database :
OpenAIRE
Journal :
La Revue de medecine interne
Accession number :
edsair.pmid..........b4f0c5a8adf0ab980ec37f06aba6e86b