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Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [

Authors :
Xiaotian T, Fang
Jonas, Eriksson
Gunnar, Antoni
Ulrika, Yngve
Linda, Cato
Lars, Lannfelt
Dag, Sehlin
Stina, Syvänen
Source :
Neuropharmacology. 113
Publication Year :
2016

Abstract

Alzheimer's disease (AD) is characterized by aggregation of amyloid beta (Aβ) into insoluble plaques. Intermediates, Aβ oligomers (Aβo), appear to be the mechanistic cause of disease. The de facto PET AD ligand, [

Details

ISSN :
18737064
Volume :
113
Database :
OpenAIRE
Journal :
Neuropharmacology
Accession number :
edsair.pmid..........b370d8f2dfca34ac973271db71eaef4e