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Tumor Necrosis Factor-α Increases Claudin-1, 4, and 7 Expression in Tubular Cells: Role in Permeability Changes
- Source :
- Journal of cellular physiology. 232(8)
- Publication Year :
- 2016
-
Abstract
- Tumor necrosis factor-α (TNFα), is a pathogenic cytokine in kidney disease that alters expression of claudins in tubular cells. Previously we showed that in LLC-PK
- Subjects :
- Time Factors
Swine
Tumor Necrosis Factor-alpha
JNK Mitogen-Activated Protein Kinases
Transfection
Permeability
Up-Regulation
Intercellular Junctions
Kidney Tubules
Claudin-1
Electric Impedance
Animals
LLC-PK1 Cells
Claudin-2
RNA Interference
RNA, Messenger
Claudin-4
Extracellular Signal-Regulated MAP Kinases
Signal Transduction
Subjects
Details
- ISSN :
- 10974652
- Volume :
- 232
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Journal of cellular physiology
- Accession number :
- edsair.pmid..........b363bde44ba82a76326ed3dd3caa9a9a