Sonochemical synthesis and biological evaluation of isoquinolin-1(2H)-one/isoindolin-1-one derivatives: Discovery of a positive ago-allosteric modulator (PAAM) of 5HT

Authors :: Jetta, Sandeep Kumar
Rapaka, Naimisha
B, Thirupataiah
Gangireddy, Sujeevan Reddy
Navneet, Bung
Arijit, Roy
Gopalakrishnan, Bulusu
Ankita, Mishra
Prem N, Yadav
Parimal, Misra
Manojit, Pal
Source :: Bioorganic chemistry. 129
Publication Year :: 2022
Abstract: Efforts have been devoted for the discovery and development of positive allosteric modulators (PAMs) of 5-HT

Subjects :: Male
Mice
Mice, Inbred BALB C
Indoles
Animals
Brain
Isoquinolines
Serotonin 5-HT2 Receptor Agonists
Rats

Tools