Back to Search
Start Over
Expression and prognostic significance of heat-shock proteins in myelodysplastic syndromes
- Source :
- Haematologica. 91(5)
- Publication Year :
- 2006
-
Abstract
- Using flow cytometry, we investigated the clinical and hematologic relevance of expression of heat-shock proteins (HSP) HSP27, HSP60, HSP70, HSP90 and HSP110 in bone marrow of 142 patients with newly diagnosed myelodysplastic syndromes, together with that of the membrane differentiation antigen CD34 and the drug-resistance related protein, P170 (Pgp).
- Subjects :
- Adult
Aged, 80 and over
Male
ATP Binding Cassette Transporter, Subfamily B
bcl-X Protein
Antigens, CD34
Apoptosis
Middle Aged
Flow Cytometry
Prognosis
Severity of Illness Index
Survival Analysis
Genes, bcl-2
Hematopoiesis
Gene Expression Regulation
Proto-Oncogene Proteins c-bcl-2
Leukemia, Myeloid
Myelodysplastic Syndromes
Acute Disease
Disease Progression
Humans
Female
Heat-Shock Proteins
Aged
Glycoproteins
Subjects
Details
- ISSN :
- 15928721
- Volume :
- 91
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Haematologica
- Accession number :
- edsair.pmid..........b1e1ffee559a2d36d8201757a0bf5bf1