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Liver ultrastructural changes following portal circulation disturbances
- Source :
- Morphologie et embryologie. 27(1)
- Publication Year :
- 1981
-
Abstract
- Liver cell changes produced in rats by the ligature of the portal vein and of the spleen pedicle were studied by electron microscopy. There were differences in the liver response to the various types of circulatory disturbances. The earliest and most marked lesions of hepatic cells were noticed in the case of portal vein ligature, and occurred at the level of rough endoplasmic reticulum, mitochondria and lysosomes. No significant changes in Kupffer cells. When the spleen pedicle was ligated, the hepatic cell changes were less obvious, but the Kupffer cells changes were more prominent, testifying and increased hetero- and autophagy.
- Subjects :
- Portal System
Liver
Liver Diseases
Animals
Liver Circulation
Rats
Subjects
Details
- ISSN :
- 03775038
- Volume :
- 27
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Morphologie et embryologie
- Accession number :
- edsair.pmid..........b1a15e506306468a6d12bfc76fd1fcbe