Therapeutic Delivery of miR-143 Targeting Tumor Metabolism in Poorly Differentiated Thyroid Cancer Xenografts and Efficacy Evaluation Using

Authors :: Ying, Miao
Ling-Fei, Zhang
Min, Zhang
Rui, Guo
Mo-Fang, Liu
Biao, Li
Source :: Human gene therapy. 30(7)
Publication Year :: 2019
Abstract: Poorly differentiated thyroid carcinoma cells tend to be more aggressive and show enhanced glucose uptake which could be exploited for anti-cancer strategy. Previously, we identified hexokinase 2 (

Subjects :: Gene Transfer Techniques
Apoptosis
Genetic Therapy
X-Ray Microtomography
Disease Models, Animal
Mice
MicroRNAs
Cell Movement
Fluorodeoxyglucose F18
Positron Emission Tomography Computed Tomography
Animals
Heterografts
Humans
Thyroid Neoplasms
Neoplasm Grading
Energy Metabolism
Glycolysis
Cell Proliferation

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