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[A Case of an Asymptomatic Coagulopathy after Peritoneovenous Shunt Placement for Malignant Ascites of Gastric Cancer]

Authors :
Tetsuya, Asakawa
Hiroto, Saito
Mari, Shimada
Takahisa, Yamaguchi
Shiro, Terai
Koichi, Okamoto
Jun, Kinoshita
Keishi, Nakamura
Itasu, Ninomiya
Sachio, Fushida
Source :
Gan to kagaku ryoho. Cancerchemotherapy. 48(4)
Publication Year :
2021

Abstract

The patient was a 61‒year‒old man who had an advanced gastric cancer with peritoneal dissemination. After chemotherapy, intraoperative findings during a total gastrectomy revealed the disappearance of the dissemination nodules. Although adjuvant chemotherapy was performed, the presence of massive ascites led to the recurrence of the peritoneal dissemination 5 months after the surgery. While the chemotherapy regimen was altered, we observed no reduction in malignant ascites. The patient complained of abdominal distention and was admitted to our hospital for symptom management. We performed a cell‒free and concentrated ascites reinfusion therapy(CART)several times. However, symptom management proved difficult; therefore, the patient underwent a peritoneovenous shunt(Denver shunt)placement. After the shunting, we observed no organ injury and improved abdominal distention; however, an asymptomatic coagulopathy was present in the course. Additionally, blood examinations showed increased FDP‒DD and thrombin‒antithrombin complex(TAT). However, 6 months after the shunting, coagulopathy improved and the patient reported the absence of abdominal distention. This report describes a patient with an asymptomatic coagulopathy after Denver shunt placement and evaluated the clinical course by using TAT values.

Details

ISSN :
03850684
Volume :
48
Issue :
4
Database :
OpenAIRE
Journal :
Gan to kagaku ryoho. Cancerchemotherapy
Accession number :
edsair.pmid..........abdd684350d09aaf03265e912494a9c8