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Identification of

Authors :
Ryan, Moslin
Yanlei, Zhang
Stephen T, Wrobleski
Shuqun, Lin
Michael, Mertzman
Steven, Spergel
John S, Tokarski
Joann, Strnad
Kathleen, Gillooly
Kim W, McIntyre
Adriana, Zupa-Fernandez
Lihong, Cheng
Huadong, Sun
Charu, Chaudhry
Christine, Huang
Celia, D'Arienzo
Elizabeth, Heimrich
Xiaoxia, Yang
Jodi K, Muckelbauer
ChiehYing, Chang
Jeffrey, Tredup
Dawn, Mulligan
Dianlin, Xie
Nelly, Aranibar
Manoj, Chiney
James R, Burke
Louis, Lombardo
Percy H, Carter
David S, Weinstein
Source :
Journal of medicinal chemistry. 62(20)
Publication Year :
2019

Abstract

As a member of the Janus (JAK) family of nonreceptor tyrosine kinases, TYK2 plays an important role in mediating the signaling of pro-inflammatory cytokines including IL-12, IL-23, and type 1 interferons. The nicotinamide

Details

ISSN :
15204804
Volume :
62
Issue :
20
Database :
OpenAIRE
Journal :
Journal of medicinal chemistry
Accession number :
edsair.pmid..........a6a5ff3f143a4460f1c63e1a663ab705