[Prognostic significance of groin lymph node ratio in vulvar squamous cell carcinoma]

The aim was to review the clinical impact of lymph node ratio (LNR) of groin metastatic nodal disease in women with vulvar squamous cell carcinoma.Cohort study of women with vulvar squamous cell carcinoma, managed between January 2005 and December 2015, in five institutions in France with prospectively maintained databases (French multicenter tertiary care centers).In total, 636 women managed for VSCC of whom 508 (79.9%) underwent surgical groin nodal staging.Comparison of overall and recurrence free survival between women according to LNR.In total, 176 women (34.6%) had at least one positive lymph node (LN). There was a significant differences for the 5-year overall survival and recurrence free survival rates between women with LNR0.2 and women with LNR0.2.LNR seems to be a significant prognostic factor in women with vulvar squamous cell carcinoma.