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[Active tuberculosis in a cohort of HIV-infected inmates in a prison in Mexico City: clinical and epidemiological characteristics]

Authors :
Christian, Hernández-León
Florentino, Badial-Hernández
Alfredo, Ponce-de-León
Juan G, Sierra-Madero
Areli, Martínez-Gamboa
Brenda, Crabtree-Ramírez
Sergio, Bautista-Arredondo
Adrián, González-Aguirre
María de Lourdes, Guerrero-Almeida
J Miriam Bobadilla, del Valle
Andrea, González-Rodríguez
José, Sifuentes-Osornio
Source :
Salud publica de Mexico. 54(6)
Publication Year :
2011

Abstract

To determine the clinical and epidemiological characteristics of prison inmates with active tuberculosis in HIV-positive prison populations.We conducted a cohort study in HIV-infected subjects in a prison in Mexico City, with the aim of determining clinical and epidemiological characteristics of cases with active TB.We detected 172 HIV infected inmates and TB in 28 of them (16.3%) - 21 (12.2) with pulmonary TB--with an incidence rate of 7.7/100 persons/year for active TB and 4.7/100 persons/year for pulmonary TB. No drug resistance was found. Two clusters (4 and 2 subjects) were observed after RFLP-typing of 18 isolates, with a transmission rate of 11% by molecular and clinical analysis.The prevalence of active TB was found to be a thousand times greater than in the general population. Evidence of transmission inside the prison was also found.

Details

ISSN :
16067916
Volume :
54
Issue :
6
Database :
OpenAIRE
Journal :
Salud publica de Mexico
Accession number :
edsair.pmid..........a1771ed9b4b91f23736d261122201cb3