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[Effect of L-lysine-a-oxidase on reproduction of herpes simplex type I virus in vitro]

Authors :
I P, Smirnova
S V, Diorditsa
S B, Alekseev
I Z, Zaĭtsev
Source :
Voprosy meditsinskoi khimii. 44(4)
Publication Year :
1998

Abstract

L-lysin-a-oxidase (LO), a fungal enzyme catalysing oxidative deamination of L-lysin, was used for the inhibition of the reproduction of herpes simplex virus type 1 (HSV-1). Antiviral activity of LO was tested in vitro. The expression of viral antigens and CPE of HSV-1 was inhibited by LO at a concentration 0.7 mg/ml.

Details

ISSN :
00428809
Volume :
44
Issue :
4
Database :
OpenAIRE
Journal :
Voprosy meditsinskoi khimii
Accession number :
edsair.pmid..........9d6a8855375a7e8f5c44d4152714cc60