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Infection with Staphylococcus aureus elicits COX-2/PGE
- Source :
- Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 107
- Publication Year :
- 2018
-
Abstract
- Staphylococcus aureus (S. aureus) can lead to many life-threatening diseases. It has the ability to invade normal endovascular tissue. The molecular mechanisms and pathological changes of endothelial cells after S. aureus infection are of interest, but the basic understanding of how S. aureus destroys this barrier is not clear. Here, we showed that S. aureus enhanced COX-2 expression and prostaglandin E
- Subjects :
- Inflammation
Male
Mitogen-Activated Protein Kinase 1
Staphylococcus aureus
Mitogen-Activated Protein Kinase 3
Interleukin-6
NF-kappa B
Free Radical Scavengers
Staphylococcal Infections
p38 Mitogen-Activated Protein Kinases
Antioxidants
Dinoprostone
Rats
Rats, Sprague-Dawley
Matrix Metalloproteinase 9
Cardiovascular Diseases
Cyclooxygenase 2
Animals
Humans
Reactive Oxygen Species
Aorta
Subjects
Details
- ISSN :
- 19506007
- Volume :
- 107
- Database :
- OpenAIRE
- Journal :
- Biomedicinepharmacotherapy = Biomedecinepharmacotherapie
- Accession number :
- edsair.pmid..........9cfeb5461a88dba0f0dac469805075ce