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Evaluation of renal glucose uptake with [

Authors :
Eleni, Rebelos
Andrea, Mari
Vesa, Oikonen
Hidehiro, Iida
Pirjo, Nuutila
Ele, Ferrannini
Source :
Metabolism: clinical and experimental.
Publication Year :
2022

Abstract

Studying renal glucose metabolism non-invasively in humans is an unmet need. Positron emission tomography (PET) is the current gold standard for measuring regional tissue glucose uptake rates, but the most widely used glucose analog ([We measured individual [We found that the corrected glucose uptake is consistently higher in the medulla than cortex and that both cortical and medullary glucose uptake are higher in lean than obese participants under both fasting and insulinized conditions. Moreover, cortical but not medullary glucose uptake is increased from the fasting to the insulinized condition.The data show for the first time that [

Details

ISSN :
15328600
Database :
OpenAIRE
Journal :
Metabolism: clinical and experimental
Accession number :
edsair.pmid..........9af75263e6af05d338ef098afc3be1bc