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Using PLINK for Genome-Wide Association Studies (GWAS) and data analysis

Authors :
Miguel E, Rentería
Adrian, Cortes
Sarah E, Medland
Source :
Methods in molecular biology (Clifton, N.J.). 1019
Publication Year :
2013

Abstract

Within this chapter we introduce the basic PLINK functions for reading in data, applying quality control, and running association analyses. Three worked examples are provided to illustrate: data management and assessment of population substructure, association analysis of a quantitative trait, and qualitative or case-control association analyses.

Subjects

Subjects :
Quality Control
Models, Statistical
Phenotype
Quantitative Trait, Heritable
Genotype
Research Design
Case-Control Studies
Animals
Humans
HapMap Project
Metagenomics
Software
Genome-Wide Association Study

Details

ISSN :
19406029
Volume :
1019
Database :
OpenAIRE
Journal :
Methods in molecular biology (Clifton, N.J.)
Accession number :
edsair.pmid..........9989a76492c7811f09793aca6687a589

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Authors Abstract Subjects Details