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[Early diagnosis of late complications in juvenile diabetics]
- Source :
- Casopis lekaru ceskych. 129(7)
- Publication Year :
- 1990
-
Abstract
- In a group of 69 insulin dependent diabetics aged 19-59 years (mean 25.5 years) with a duration of diabetes of 2 to 34 years (mean 12.5) the authors assessed the incidence of diabetic retinopathy, nephropathy and neuropathy in relation to the duration of diabetes, to its long-term compensation and HLA antigens. In 45 the diabetes was manifested before the age of 15 years. The authors found a rising trend of retinopathy (12-14-25-75-86%) and neuropathy (0-50-60-85-83%) in five groups with a duration of diabetes up to 5, 10, 15, 20 and above 20 years. 15% of the patients with a duration of diabetes of more than 15 years had positive microalbuminuria or permanent proteinuria and hypertension. In diabetic patients with long-term satisfactory compensation there was a lower incidence of these complications than in patients with poorer compensation. The presence of HLA B8 antigen was associated with a prolonged favourable course of diabetes, with a lower incidence and later manifestation of complications.
- Subjects :
- Adult
Diabetic Retinopathy
Time Factors
Humans
Diabetic Nephropathies
Middle Aged
Subjects
Details
- Language :
- Czech
- ISSN :
- 00087335
- Volume :
- 129
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Casopis lekaru ceskych
- Accession number :
- edsair.pmid..........9941fd2cf98cc35d90ec1146a71c878a