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Peripheral Blood Biomarkers Associated With Toxicity and Treatment Characteristics After

Authors :
Kevin, Campbell
Erin E, Karski
Aleksandra, Olow
David A, Edmondson
Ayano C, Kohlgruber
Matthew, Coleman
Daphne A, Haas-Kogan
Katherine K, Matthay
Steven G, DuBois
Source :
International journal of radiation oncology, biology, physics. 99(2)
Publication Year :
2017

Abstract

Few tools exist to predict clinical outcomes after radiopharmaceutical therapy. Our goal was to identify associations between blood-based biomarkers of radiation effect and clinical outcomes afterWe conducted a prospective, single-center cohort study in children with advanced neuroblastoma treated withThe cohort included 40 patients (30 male/10 female; median age 7 years). We observed significant modulation of the majority of markers between baseline and hour 72 afterPeripheral blood biomarkers relevant to radiation exposure are significantly modulated during the acute period after

Details

ISSN :
1879355X
Volume :
99
Issue :
2
Database :
OpenAIRE
Journal :
International journal of radiation oncology, biology, physics
Accession number :
edsair.pmid..........94f98bccf90b04187679c757b4e4819a