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Meta-analysis of Cancer Gene Profiling Data
- Source :
- Methods in molecular biology (Clifton, N.J.). 1381
- Publication Year :
- 2015
-
Abstract
- The simultaneous measurement of thousands of genes gives the opportunity to personalize and improve cancer therapy. In addition, the integration of meta-data such as protein-protein interaction (PPI) information into the analyses helps in the identification and prioritization of genes from these screens. Here, we describe a computational approach that identifies genes prognostic for outcome by combining gene profiling data from any source with a network of known relationships between genes.
Details
- ISSN :
- 19406029
- Volume :
- 1381
- Database :
- OpenAIRE
- Journal :
- Methods in molecular biology (Clifton, N.J.)
- Accession number :
- edsair.pmid..........8f145c18cbe02dfeca4a74efedd52780