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Extracellular adenosine promotes cell migration/invasion of Glioblastoma Stem-like Cells through A

Authors :
Ángelo, Torres
Jose Ignacio, Erices
Fabiola, Sanchez
Pamela, Ehrenfeld
Laurent, Turchi
Thierry, Virolle
Daniel, Uribe
Ignacio, Niechi
Carlos, Spichiger
José Dellis, Rocha
Marcos, Ramirez
Flavio, Salazar-Onfray
Rody, San Martín
Claudia, Quezada
Source :
Cancer letters. 446
Publication Year :
2018

Abstract

Glioblastoma (GBM) is the brain tumor with the worst prognosis composed of a cell subpopulation called Glioblastoma Stem-like Cells (GSCs) responsible for tumor recurrence mediated by cell invasion. GSCs persist in a hypoxic microenvironment which promotes extracellular adenosine production and activation of the A

Details

ISSN :
18727980
Volume :
446
Database :
OpenAIRE
Journal :
Cancer letters
Accession number :
edsair.pmid..........8e51f532e481a1306af434ec29d61d6b