Tambulin from Zanthoxylum armatum acutely potentiates the glucose-induced insulin secretion via K

Authors :: Abdul, Hameed
Sayed Ali, Raza
M, Israr Khan
Janaki, Baral
Achyut, Adhikari
Mohammad, Nur-E-Alam
Sarfaraz, Ahmed
Adnan J, Al-Rehaily
Sajda, Ashraf
Zaheer, Ul-Haq
Rahman M, Hafizur
Source :: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 120
Publication Year :: 2019
Abstract: Tambulin, a flavonol isolated from Zanthoxylum armatum, showed potent insulin secretory activity in our preliminary anti-diabetic screening. Here, we explored the insulin secretory mechanism(s) of tambulin focusing in glucose-dependent, K

Subjects :: Male
Zanthoxylum
Mice, Inbred BALB C
Secretory Pathway
Tolbutamide
Cyclic AMP-Dependent Protein Kinases
Cell Line
Islets of Langerhans
Mice
Glucose
KATP Channels
Cyclic AMP
Animals
Hypoglycemic Agents
Insulin
Benzopyrans
Calcium Signaling
Ion Channel Gating

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