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The transcription factor Fli1 restricts the formation of memory precursor NK cells during viral infection

Authors :
Luke, Riggan
Feiyang, Ma
Joey H, Li
Elizabeth, Fernandez
David A, Nathanson
Matteo, Pellegrini
Timothy E, O'Sullivan
Source :
Nature immunology. 23(4)
Publication Year :
2021

Abstract

Natural killer (NK) cells are innate lymphocytes that possess traits of adaptive immunity, such as memory formation. However, the molecular mechanisms by which NK cells persist to form memory cells are not well understood. Using single-cell RNA sequencing, we identified two distinct effector NK cell (NK

Details

ISSN :
15292916
Volume :
23
Issue :
4
Database :
OpenAIRE
Journal :
Nature immunology
Accession number :
edsair.pmid..........8afd436339cb13e87c863eedf4237fe6