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Synthesis and biological evaluation of organoselenium (NSAIDs-SeCN and SeCF
- Source :
- European journal of medicinal chemistry. 208
- Publication Year :
- 2020
-
Abstract
- A series of organoselenium compounds based on the hybridization of nonsteroidal antiinflammatory drugs (NSAIDs) scaffolds and Se functionalities (-SeCN and -SeCF
- Subjects :
- Thioredoxin Reductase 1
Caspase 3
Anti-Inflammatory Agents, Non-Steroidal
Antineoplastic Agents
Apoptosis
DNA
Free Radical Scavengers
Molecular Docking Simulation
Proto-Oncogene Proteins c-bcl-2
Cell Line, Tumor
Organoselenium Compounds
Humans
Interleukin-2
Drug Screening Assays, Antitumor
DNA Damage
Protein Binding
Subjects
Details
- ISSN :
- 17683254
- Volume :
- 208
- Database :
- OpenAIRE
- Journal :
- European journal of medicinal chemistry
- Accession number :
- edsair.pmid..........87984fadda199d57dc7a5b3176a8b130