Late Diagnoses of HIV Infection in Mississippi: Implications for Improved Testing Strategies and Treatment

According to the Centers for Disease Control and Prevention, more than 1.1 million people in the United States are living, with HIV infection, and approximately 1 in 6 (18%) are unaware of their infection. People living with undiagnosed HIV are more likely to progress to AIDS, transmit the virus to others, and have poorer overall health outcomes. In 2013, Mississippi had the 6th highest estimated AIDS diagnoses rate among adults and adolescents in the United States and when comparing persons living with AIDS, the Jackson, MS metropolitan area had the tenth highest rate among all MSAs.The objective of this study is to describe people who are diagnosed with HIV late in their course of illness and to identify characteristics associated with late diagnoses.Demographic data was obtained for all Mississippi residents who were diagnosed with HIV infection between Janary 1, 2004 and December 31,2014. Late diagnoses of HIV infection is defined as an AIDS diagnosis made within 12 months from an initial HIV diagnosis. Prevalence trends, demographics, and predictors of late diagnoses were measured. Results: Among 4,864 cases of -IV disease, 35% (1,682) were late diagnoses. Late diagnoses were more likely to occur among males, individuals over the age of 34, and individuals who were diagnosed outside of Mississippi State Department of Health clinics.A large proportion of individuals had late diagnoses of HIV infection and this proportion has slightly declined in recent years. Routine testing in medical settings and in areas with high morbidity may increase early HIV diagnosis.