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[A Case of Flexion Contracture Associated with Hypopituitarism]
- Source :
- Brain and nerve = Shinkei kenkyu no shinpo. 71(6)
- Publication Year :
- 2019
-
Abstract
- A 72-year-old Japanese man developed progressive disturbance in ambulation with flexion contractures 5years before this admission. At 49 years of age, he was diagnosed with hypopituitarism after an operation for a Rathke's cleft. On admission, he could not fully extend his knees and hips because of painful muscle stiffness of the lower extremities. Initially, we suspected Stiff-person syndrome and initiated diazepam, which had no effect. Serum anti-glutamic acid decarboxylase antibody was negative. Next, we suspected flexion contractures associated with hypopituitarism. Endocrine evaluation revealed that ACTH, cortisol, and other hormone levels were lower than those reported in the previous evaluation. We treated the patient with hydrocortisone and his symptoms dramatically improved. It is rare for patients with hypopituitarism to have flexion contracture. This case suggests that we should consider hypopituitararism in the setting of flexion contractures. (Received October 18, 2018; Accepted March 26, 2019; Published June 1, 2019).
Details
- ISSN :
- 18816096
- Volume :
- 71
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Brain and nerve = Shinkei kenkyu no shinpo
- Accession number :
- edsair.pmid..........7fc77e74265ba6b912a35723acd659d2