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Molecular Imaging in Oncology: Advanced Microscopy Techniques
- Source :
- Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. 216
- Publication Year :
- 2020
-
Abstract
- Preclinical studies usually require high levels of morphological, functional, and biochemical information at subcellular resolution. This type of information cannot be obtained from clinical imaging techniques, such as MRI, PET/CT, or US. Luckily, many microscopy techniques exist that can offer this information, also for malignant tissues and therapeutic approaches. In this overview, we discuss the various advanced optical microscopy techniques and their applications in oncological research. After a short introduction in Sect. 16.1, we continue in Sect. 16.2 with a discussion on fluorescent labelling strategies, followed in Sect. 16.3 by an in-depth description of confocal, light-sheet, two-photon, and super-resolution microscopy. We end in Sect. 16.4 with a focus on the applications, specifically in oncology.
- Subjects :
- Microscopy
Neoplasms
Humans
Medical Oncology
Molecular Imaging
Subjects
Details
- ISSN :
- 00800015
- Volume :
- 216
- Database :
- OpenAIRE
- Journal :
- Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
- Accession number :
- edsair.pmid..........7d26d0365d9116c2c76085cda91f7338