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Authors :
Darwin, Elizondo-Quiroga
Lorena, Zapata-Cuellar
José Alberto, Uribe-Flores
Jorge, Gaona-Bernal
Tanya Amanda, Camacho-Villegas
Carlos Alberto, Manuel-Cabrera
María Elena, Trujillo-Ortega
Gerardo, Ramírez-Hernández
Marco Antonio, Herradora-Lozano
María Del Cármen, Mercado-García
Abel, Gutiérrez Ortega
Source :
Viral immunology. 32(9)
Publication Year :
2019

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) still poses a threat to the swine industry worldwide. Currently, commercial vaccines against PRRSV, which consist of modified live or inactivated virus, reduce symptoms and viremia in immunized pigs, but efficacy against heterologous strains is variable. This has led to the development of subunit vaccines that contain viral antigens that show the highest variability. In this work, a chimeric protein comprising short amino acid sequences from glycoprotein 3 (GP3), glycoprotein 4 (GP4), glycoprotein 5 (GP5), and M (matrix protein) proteins of PRRSV was designed and expressed in

Details

ISSN :
15578976
Volume :
32
Issue :
9
Database :
OpenAIRE
Journal :
Viral immunology
Accession number :
edsair.pmid..........7c0beb1ba530351f9671b415fea5133e