[Study of interaction between vitamin D2 and excipients by use of diffuse reflectance spectra]

The interaction of Vit D2 with calcium compounds and excipients commonly used was studied by use of diffuse reflectance spectra (DRS). The results indicated that there was some interaction between Vit D2 and calcium lactate, glucose, and a strong interaction between Vit D2 and magnesium stearate; and that the interaction between Vit D2 calcium gluconate, CaHPO4, sucrose, starch, lactose and mannitol was very weak and could even be neglected.