[STUDY OF SENSITIVITY TO ANTI-MICROBIAL AGENTS OF MICRO-ORGANISMS FROM ZONE OF PURULENT INFLAMMATION AMONG PATIENTS OF MAXILLOFACIAL HOSPITAL DEPARTMENT]

The importance of control for nosocomial and community-acquired infections is one of the priorities of practical surgery, and maxillofacial surgery is no exception in this matter. Aim of study - to determine the spectrum of antimicrobial activity of widespread antiseptics and antibacterial agents used for topical treatment of odontogenic phlegmons of the maxillofacial region. A bacteriological study of purulent wound exudate was carried out for 109 patients of the maxillofacial hospital department with a diagnosis of odontogenic phlegmons. Using the method of "draw-wells" the sensitivity of the isolated bacterial cultures to solutions of decamethoxin, dioxidine, formaldehyde, and sanguiritrin was determined. Using the dilution method microbicide concentrations of decamethoxin and miramistin were determined by influencing the clinical and museum strains of pathogenic bacteria. In purulent exudate the monocultures of staphylococci were determined - 79 (40.1%), and streptococci - 86 (43.65%), aerobic non-fermenting bacteria - 11 (5.60%) and enterobacteria - 21 (10,65%) were found much less often. Isolated from S. aureus and E. coli proved to be sensitive to solutions of decamethoxin, formaldehyde and sanguiritrin; isolated strains of P. aeruginosa - only to decamethoxin and formaldehyde. Microbicide concentrations of decamethoxin were 4-35 times lower than miramistin due to effect on clinical and museum strains of bacteria. Efficiency of decamethoxin was higher.